December 07−08, 2022, Berlin
(Hybrid congress)

GA2LEN Global Urticaria Forum

December 09−11, 2021, Hiroshima, Japan
(Hybrid congress)

GA2LEN UCARE Urticaria Conference

GA²LEN Global Urticaria Forum/ UCARE

Poster icon

Remibrutinib improves quality of life in CSU patients

M. Maurer, A.M. Giménez-Arnau, V. Jain, J. Tillinghast, A. Tolcachier, S. Nigen, K. Hayama,
K. Lheritier, P. Walsh, S. Haemmerle
Poster icon

Remibrutinib for chronic spontaneous urticaria: Time to complete urticaria control

P. Staubach, M. Maurer, P. Yamauchi, H. Kanavy, A.M. Giménez-Arnau, J. Reed, K. Lheritier,
P. Walsh, I. Nikolaev, S. Haemmerle, M. Lebwohl
Poster icon

More patients achieve absence of angioedema with remibrutinib than placebo

M. Maurer, J. Reed, P. Staubach, K. Lheritier, P. Walsh, I. Nikolaev, S. Haemmerle, A. Giménez-Arnau
Poster icon

Remibrutinib reduces the use of rescue medication in CSU patients

P. Staubach, M. Maurer, J. Reed, K. Lheritier, P. Walsh, I. Nikolaev, S. Haemmerle, A.M. Giménez-Arnau
Poster icon

Long-term safety and tolerability of remibrutinib in CSU patients

A.M. Giménez-Arnau, M. Maurer, M. Metz, V. Jain, P. Walsh, K. Lheritier, S. Hugot, H. Zouater,
S. Haemmerle, A. Zharkov
Poster icon

No increase of infections and infestations with remibrutinib in CSU

M. Metz, A.M. Giménez-Arnau, M. Maurer, A. Tolcachier, S. Haemmerle, K. Lheritier, A. Zharkov
Poster icon

Remibrutinib versus placebo in CSU patients: REMIX-1 and REMIX-2 trials

M. Hide, M. Maurer, A.M. Giménez-Arnau, S. Saini, M. Lebwohl, G. Sussman, E.D. Martzloff,
K. Lheritier, A. Zharkov, S. Haemmerle
Poster icon

Remibrutinib improves CSU in patients with low or high IgE

M. Hide, K. Hayama, A. Ramsey, M. Maurer, K. Lheritier, A. Zharkov, S. Haemmerle, I. Nikolaev
Poster icon

Remibrutinib improves CSU irrespective of baseline
CU-Index status

M. Maurer, W. Carr, K. Sitz, V. Jain, A.M. Giménez-Arnau, K. Lheritier, I. Nikolaev, S. Haemmerle
Poster icon

Remibrutinib improves sleep and activity in patients with CSU

A.M. Giménez-Arnau, L. Clore, V. Jain, K. Lheritier, P. Walsh, S. Haemmerle, M. Maurer
Poster icon

Ligelizumab in chronic spontaneous urticaria: Phase-3 PEARL study results

A.M. Giménez-Arnau, M. Maurer, G. Sussman, S. Saini, M. Hide, L.F. Ensina, V. Varanasi, A. Barve, E. Scosyrev, A. Burciu, E. Hua, M. Patekar, T. Severin
Poster icon

Angioedema control in CSU correlates with improved health-related QoL

M. Metz, A.M. Giménez-Arnau, M. Maurer, M. Hide, K. Sitz, C.E. Ortmann, M.M. Balp, T. Severin
Poster icon

Contextual factors analysis guiding an implementation science study in CSU

P.A. Laires, M. Bartezaghi, O. Bonavita, E. Peruzzi, G. Dasari, N. Janssens, V. Herrera, E. Gibbons, J.N. Hill, C. Smith, I. Nikolaev, S. De Geest
Poster icon

Low QoL scores on UCT associated with poor antihistamine response

A. Rajan, P.A. Laires, N. Janssens, S. Rizvi, S. Smeets, A.M. Giménez-Arnau, K. Weller
Poster icon

Low UCT scores predicted higher probability of poor antihistamine response

P.A. Laires, A. Rajan, N. Janssens, S. Rizvi, S. Smeets, K. Weller, A.M. Giménez-Arnau
Poster icon

Low UCT scores predict poor antihistamine response in CSU

A. Rajan, P.A. Laires, N. Janssens, S. Rizvi, S. Smeets, K. Weller
Poster icon

Urticaria voices: Patients’ and physicians’ perceptions of chronic urticaria

P.A. Laires, M.M. Balp, K. Weller, T.A. Winders, J.A. Bernstein, J.E.M. O’Donoghue, J. Kleebach,
L. Christen, S. Smeets
Poster icon

CSU has a similar impact on QoL as plaque psoriasis

I. Nikolaev, N. Barbier, C.E. Ortmann, N. Janssens, N. Chapman-Rothe, N. Hajizadeh, O. Hsine,
A. Rajan, P.A. Laires, H. Edgren
Poster icon

Impact of CSU on patients’ lives: Social media listening analysis

E. Kocaturk, M. Bizjak, E.S. Baldrich, L. Walter, P.T. Montana, L. Christen, N. Janssens, S. Smeets
Poster icon

PREDICT-CU: Predicting time to clinical remission in chronic urticaria

I. Pivneva, M.M. Balp, Y. Geissbühler, T. Severin, S. Smeets, J. Signorovitch, T. Cornwall,
A. Danyliv, S. Walsh, W. Soong, A. Marsland
Poster icon

Remission and comorbidities in chronic spontaneous and chronic inducible urticaria

I. Pivneva, M.M. Balp, A. Danyliv, K. Chen, T. Cornwall, J. Signorovitch, T. Severin, W. Soong,
A. Marsland
Poster icon

Burden of angioedema in European patients with chronic spontaneous urticaria

M.M. Balp, K. Krupsky, B.L. Balkaran, S. Gupta, C. Lienhard, J. Loh, J. M. Rodriguez Barrios,
A. Romero, D. Patil, S. Walsh, R.K. Kohli, F. Tétart, T. El-Shanawany, J. Reed
Poster icon

Comparative economic burden of chronic spontaneous urticaria, psoriasis, atopic dermatitis

S. Gupta S., M.M. Balp, S. Walsh, B.L. Balkaran, C. Lienhard, J. Loh, J. M. Rodriguez Barrios,
K. Krupsky, A. Romero, T. El-Shanawany, F. Tétart, J. Reed
Poster icon

Comparative humanistic burden of chronic spontaneous urticaria, psoriasis, atopic dermatitis

M.M. Balp, S. Walsh, B.L. Balkaran, S. Gupta, K. Krupsky, C. Lienhard, J. Loh, J. M. Rodriguez Barrios, A. Romero, F. Tétart, T. El-Shanawany, J. Reed
Poster icon

Ligelizumab achieves freedom from CSU-symptoms regardless of previous H1-antihistamine dose

A. M. Giménez-Arnau, M. Maurer, W. Soong, K. Sitz, J. A. Bernstein, E. Hua, T. Severin
Poster icon

Ligelizumab further improves disease-activity in CSU patients previously on omalizumab

M. Hide, M. Maurer, K. Sitz, G. Sussman, M. Metz, N. Barbier, E. Hua, T. Severin
Poster icon

Ligelizumab further improves sleep in CSU patients previously on omalizumab

M. Metz, A. Giménez-Arnau, M. Hide, M. Maurer, K. Sitz, G. Sussman, N. Barbier, E. Hua, M-M. Balp, T. Severin
Poster icon

Ligelizumab achieves fast symptom control in CSU: Rolling UAS7 analysis

J. A. Bernstein, M. Hide, M. Maurer, A. Giménez-Arnau, W. Soong, S. Acharya, A. Barve, T. Severin
Poster icon

Complete response with ligelizumab in CSU: A composite score analysis

M. Hide, A. Giménez-Arnau, M. Maurer, J. A. Bernstein, K. Sitz, G. Sussman, P. T. Montana, S. Acharya, T. Severin
Poster icon

Ligelizumab for adolescent CSU patients: A dedicated Phase 2b study

P. Staubach, B. E. Sekerel, M. Alvaro-Lozano, M. Maurer, M. Ben-Shoshan, A. Drollmann, A. Bienczak, M. Porter, T. Liu, A. Burciu, T. Severin
Poster icon

Ligelizumab shows good stability of response in CSU: Flare-up analysis

M. Maurer, A. Giménez-Arnau, M. Metz, K. Sitz, S. Acharya, N. Barbier, A. Barve, T. Severin
Poster icon

Complete symptom control is associated with improved health-related-quality-of-life in CSU

M. Maurer, A. Giménez-Arnau, J. A. Bernstein, P. Staubach, N. Barbier, E. Hua, Y. Joubert, M-M. Balp, T. Severin
Poster icon

Ligelizumab in chronic inducible urticaria: Phase-3 study design and rationale

M. Metz, M. Bizjak, T. Hawro, S. Altrichter, M. Maurer, S. S. Saini, G. Sussman, A. Giménez-Arnau, M. Hide, A. Barve, M. Porter, S. Smeets, T. Liu, E. Hua, M. Patekar, T. Severin
Poster icon

QoL of CSU patients refractory to H1- antihistamine: AWARE-LACan study

L. F. C. Ensina, F. Dabove, M. Velásquez-Lopera, L. M. T. Quijano, F. DiTata, P. Tassinari
Poster icon

Pooled analysis of AWARE, LaCAN and AMAC studies: CSU insights

A. M. Giménez-Arnau, M. Maurer, L. F. Ensina, C-Yu Chu, X. Jaumont, P. Tassinari
Poster icon

Early and sustained treatment with omalizumab significantly improves quality of life in patients with chronic spontaneous urticaria: Analysis from a worldwide real-world database (AWARE Study)

P. A. Laires, N. Janssens, A. Kandra, N. Barbier, C. E. Ortmann, S. Smeets, M-M. Balp, K. Weller
Poster icon

Complete control of wheals and itch in CSU significantly correlates with better sleep quality: Analysis from a worldwide real-world database (AWARE Study)

P. A. Laires, N. Janssens, A. Kandra, N. Barbier, C. E. Ortmann, S. Smeets, M-M. Balp, K. Weller
Poster icon

Complete control of wheals and itch in CSU significantly correlates with better patients’ quality of life: Analysis from a worldwide real-world database (AWARE Study)

P. A. Laires, N. Janssens, A. Kandra, N. Barbier, C. E. Ortmann, S. Smeets, M-M. Balp, K. Weller
Poster icon

Predicting time to remission and identifying influencing factors from a machine learning real-world study

M-M. Balp, I. Pivneva, Y. Geissbühler, T. Severin, S. Smeets, J. Signorovitch, J. Royer, Y. Liang, T. Cornwall, J. Pan, A. Danyliv, W. Soong, A. Marsland
Poster icon

Clinical profiles of patients with CSU - a real-world study in the United States

M-M. Balp, Y. Geissbühler, A. Mcconnon, J. Schäl, J. Gomme, P. A. Laires, S. J. McKenna, W. Soong
Poster icon

Clinical profiles of patients with chronic inducible urticaria: A real-world study in the USA

Y. Geissbühler, M-M. Balp, A. Mcconnon, J. Schäl, J. Gomme, P. A. Laires, S. J. McKenna, W. Soong
Poster icon

Prevalence and burden of chronic inducible urticaria in Japan

M. Hide, A. Uda, S. Tanaka, F. Maki, N. Miyakawa, S. J. McKenna, S. Gupta, B. Balkaran, M-M. Balp
Poster icon

Prevalence and burden of chronic spontaneous urticaria in Japan

M. Hide, A. Uda, S. Tanaka, F. Maki, N. Miyakawa, S. J. McKenna, S. Gupta, B. Balkaran, M-M. Balp
Poster icon

The bruton’s tyrosine kinase inhibitor remibrutinib (LOU064) in chronic spontaneous urticaria: Top line results of a Phase 2b dose-finding study

M. Maurer, A. Giménez-Arnau, W. Berger, V. Jain, K. Hayama, A. Reich, S. Haemmerle, P. Walsh, K. Lheritier, S. Xia, J. Storim

2020

Poster icon

Moderate-to-severe CSU patients achieve high complete response rate with ligelizumab

M. Maurer, J.A. Bernstein, A. Giménez-Arnau, W. Soong, G. Sussman, M. Metz, K. Sitz, M. Hide, E. Hua, A. Barve, T. Severin, R. Janocha
Poster icon

Ligelizumab retreatment achieves high rate of complete response in CSU

M. Metz, M. Maurer, A. Giménez-Arnau, W. Soong, J.A. Bernstein, G. Sussman, M. Hide, K. Sitz, E. Hua, A. Barve, T. Severin, R. Janocha
Poster icon

Long-term ligelizumab treatment maintains post-treatment symptom-control in CSU patients

A. Giménez-Arnau, M. Metz, W. Soong, J.A. Bernstein, G. Sussman, K. Sitz, M. Maurer, E. Hua, A. Barve, T. Severin, R. Janocha
Poster icon

Ligelizumab in CSU: Design and rationale of Phase-3b extension study

T. Severin, M. Maurer, A. Giménez-Arnau, M. Hide, G. Sussman, S.S. Saini, E. Hua, A. Barve, Y. Joubert, I. Indermuehle, R. Janocha
Poster icon

Ligelizumab is effective in CSU patients incompletely controlled with omalizumab

M. Metz, M. Hide, G.L. Sussman, K. Sitz, M. Maurer, T. Severin, R. Janocha, E. Hua
Poster icon

Fast and complete symptom control with ligelizumab in CSU

A. Giménez-Arnau, M. Maurer, W. Soong, M. Hide, J.A. Bernstein, E. Hua, A. Barve, T. Severin, R. Janocha
Poster icon

Sleep-interference and urticaria symptoms correlated in the ligelizumab Phase-2b study

A. Giménez-Arnau, M. Maurer, J.A. Bernstein, T. Severin, R. Janocha, M-M Balp, E. Hua
Poster icon

Complete CSU control with ligelizumab helps normalize quality of life

M. Maurer, J.A. Bernstein, A. Giménez-Arnau, W. Soong, M. Metz, N. Barbier, A. Barve, T. Severin, M.-M. Balp, R. Janocha
Poster icon

Quality-of-Life correlates with urticaria symptom control: Ligelizumab Phase-2b study data

M. Maurer, A. Giménez-Arnau, J.A. Bernstein, T. Severin, R. Janocha, M-M. Balp, E. Hua
Poster icon

Exploratory multivariate analysis to predict ligelizumab treatment outcome in CSU

M. Maurer, A. Giménez -Arnau, G. Sussmann, W. Soong, J.A. Bernstein, E. Hua, T. Liu, A. Barve, R. Janocha, T. Severin

2019

Poster icon

More patients treated with ligelizumab are angioedema-free compared with omalizumab: Results of a phase 2b clinical trial

A. Giménez-Arnau, G. Sussman, M. Maurer, E. Hua, K. Kobayashi, T. Severin, R. Janocha, M-M. Balp
Poster icon

Ligelizumab achieves sustained control of chronic spontaneous urticaria symptoms of hives, itch and angioedema: 1-year treatment results

J.A. Bernstein, D. Baker, M. Maurer, A. Giménez-Arnau, G. Sussman, A. Barve, E. Hua, T. Severin, R. Janocha
Poster icon

Ligelizumab reduces rescue medication use in patients with chronic spontaneous urticaria: Phase 2b study results

K. Sitz, W. Soong, B. Lanier, K. Kobayashi, A. Barve, E. Hua, T. Severin, R. Janocha
Poster icon

Ligelizumab Re-treatment is Highly Effective in Patients with Chronic Spontaneous Urticaria

M. Metz, D. Baker, C. Chu, I. Danilycheva, E. Hua, K. Kobayashi, T. Severin, R. Janocha
Poster icon

Ligelizumab retreatment is highly effective in patients with chronic spontaneous urticaria

M. Maurer, A. Giménez-Arnau, G. Sussman, E. Hua, T. Severin, R. Janocha
Poster icon

Ligelizumab is well tolerated and exhibits a safety profile similar to omalizumab and placebo in patients with chronic spontaneous urticaria

G. Sussman, M. Maurer, A. Giménez-Arnau, E. Hua, T. Severin, R. Janocha
Poster icon

Results from the phase 2b study demonstrate that ligelizumab achieves sustained control of CSU symptoms during treatment-free follow-up

S. Savic, G. Sussman, J.A. Bernstein, J. Hebert, C. Katelaris, E. Hua, A. Barve, T. Severin, R. Janocha
Poster icon

Study design and rationale of a phase 2b dose-finding study of ligelizumab (QGE031) in adolescent patients with chronic spontaneous urticaria

B. E. Sekerel, A. Drollmann, M. Porter, N. Kataoka, S. Koehne-Voss, M. Maurer, P. Staubach, M. Ben-Shoshan, T. Severin, R. Janocha
Poster icon

Dose-finding Phase 2 study to evaluate efficacy and safety of the novel BTK inhibitor LOU064 in patients with CSU inadequately controlled by H1-antihistamines

J. Storim, K. Lheritier, S. Hugot, P. End, B. Bieth, B. Cenni, M. Kaul, A. Gimenez-Arnau, M. Maurer, T. Severin

2018

Poster icon

High Burden of CSU in a Ligelizumab Phase 2b Study

M. Maurer, A. Giménez -Arnau, G. Sussman, J. Loeffler, A. Barve, E. Hua, M.M. Balp, T. Severin, R. Janocha
Poster icon

Next generation anti-IgE antibody Ligelizumab in CSU: Phase 2b results

M. Maurer, A. Giménez -Arnau, G. Sussman, J. Loeffler, A. Barve, T. Severin, R. Janocha
Poster icon

Ligelizumab versus omalizumab in CSU: Phase 3 design and rationale

T. Severin, M. Maurer, A. Giménez -Arnau, G. Sussman, S. Saini, M. Hide, P. Busse, K. Kobayashi, A. Barve, E. Hua, N. Kataoka, R. Janocha
© Copyright 2023 Novartis Pharma AG